Antipsychotics and their Side Effects

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Edition: 1st
Format: Paperback
Pub. Date: 2010-12-13
Publisher(s): Cambridge University Press
List Price: $92.00

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Summary

With the remarkable expansion in the use of antipsychotics, concerns about their immediate, intermediate, and long-term adverse effects have intensified. Despite this, studies consistently show that monitoring of patients taking antipsychotics can be inadequate, haphazard, or worse. This book provides a comprehensive review of the adverse effects of this pharmacologically complex therapeutic class, covering all commonly used conventional and atypical agents. In the first section, each chapter provides background information about an adverse effect, reviews the evidence linking the effect to various antipsychotics, and provides specific detection and monitoring recommendations. The second section provides unique monitoring guides for each antipsychotic. The third section provides the clinician with a program to monitor patients over the long-term. By supporting rational treatment decisions and systematic adverse effect monitoring, Antipsychotics and Their Side Effects provides the clinician with the necessary information and tools for optimizing the safe and effective long-term use of antipsychotic drugs.

Author Biography

David M. Gardner is Professor, Department of Psychiatry, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. Michael D. Teehan is Associate Professor, Department of Psychiatry, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Table of Contents

Forewordp. ix
Prefacep. xiii
Acknowledgementsp. xvi
Purpose, development, and limitations of Antipsychotics and their Side Effectsp. xviii
Guide to using Antipsychotics and their Side Effectsp. xx
Lists of appendices, figures, tables, and monitoring schedulesp. xxii
About the authorsp. xxv
About the cover artp. xxvii
Antipsychotic side effects and monitoring implicationsp. 1
Introductionp. 3
Agranulocytosis and other blood dyscrasiasp. 12
Anticholinergic effectsp. 18
Diabetes mellitusp. 24
Dyslipidemiap. 31
Extrapyramidal symptomsp. 39
Hepatic effectsp. 53
Neuroleptic malignant syndromep. 59
Obesity and weight gainp. 62
Ocular effectsp. 69
Prolactin effectsp. 74
QTc prolongation, arrhythmias, and sudden cardiac deathp. 80
Sedation and sleep disturbancesp. 89
Seizuresp. 98
Sexual dysfunctionp. 104
Sialorrheap. 112
Skin and hypersensitivity reactionsp. 118
Tardive dyskinesia and other late-onset movement disordersp. 123
Urinary incontinencep. 129
Venous thromboembolismp. 135
Vital signsp. 141
Summary of monitoring recommendations for individual antipsychoticsp. 149
Aripiprazolep. 151
Chlorpromazinep. 152
Clozapinep. 153
Flupenthixolp. 154
Fluphenazinep. 155
Haloperidolp. 156
Loxapinep. 157
Methotrimeprazinep. 158
Molindonep. 159
Olanzapinep. 160
Paliperidonep. 161
Pericyazinep. 162
Perphenazinep. 163
Pimozidep. 164
Pipotiazine palmitatep. 165
Quetiapinep. 166
Risperidonep. 167
Thioridazinep. 168
Thiothixenep. 169
Trifluoperazinep. 170
Ziprasidonep. 171
Zuclopenthixolp. 172
General monitoring form for patients taking antipsychoticsp. 173
Overview of the General Antipsychotic Monitoring Formp. 175
Frequendy asked questionsp. 176
Guide for using the General Antipsychotic Monitoring Formp. 177
Indexp. 185
Table of Contents provided by Ingram. All Rights Reserved.

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