Introduction to Ecological Genomics

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Edition: 2nd
Format: Hardcover
Pub. Date: 2012-01-13
Publisher(s): Oxford University Press
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Summary

The genomics revolution has expanded from its origins in molecular biology to impact upon every discipline in the life sciences, including ecology. Several lines of ecological research can now be profitably addressed using genomics technology, including issues of nutrient cycling, population structure, life-history variation, trophic interaction, stress responses, and adaptation to environmental change. This new edition addresses a series of fundamental ecological questions: the relationship between community structure and ecological function in ecosystems; how variation in life-history patterns among species can be explained from interaction between the genome and the environment; the molecular responses to changing and toxic environmental conditions; adaptive phenotypes and their relationship to genetic variation. Each of these questions is evaluated in the light of recent advances in genomics research, paying particular attention to data obtained from sequencing and screening of environmental genomes (metagenomics), microarray-based transcription profiling, gene expression directed by signal-transduction pathways, and the analysis of genomic polymorphisms. The chapters covering these key areas are preceded by discussions of genomics methodology (including an overview of next-generation sequencing technologies) and comparative genomics, and the book concludes with a chapter on integrative approaches such as ecological control analysis. The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models. An Introduction to Ecological Genomicsincorporates a balance of plant, animal, and microbial examples, and continues to define the new and exciting field of ecological genomics.

Table of Contents

Ecological genomics and genome analysisp. 1
The genomics revolution invading ecologyp. 1
Yeast, fly, worm, and weedp. 3
-Omics speakp. 9
Genome analysisp. 15
Comparing genomesp. 38
Properties of genomesp. 38
Prokaryotic genomesp. 52
Eukaryotic genomesp. 64
Structure and function in communitiesp. 96
The biodiversity and ecosystem functioning synthetic frameworkp. 96
Measurement of microbial biodiversityp. 98
Microbial genomics of biogeochernical cyclesp. 113
Reconstruction of functions from environmental genomesp. 129
Genomic approaches to biodiversity and ecosystem function: an appraisalp. 146
Life-history patternsp. 148
The core of life-history theoryp. 148
Longevity and agingp. 153
Gene-expression profiles in the life cyclep. 167
Phenotypic plasticity of life-history traitsp. 182
Genomic approaches to life-history patterns: an appraisalp. 192
Stress responsesp. 195
Stress and the ecological nichep. 195
The main defence mechanisms against cellular stressp. 198
Heat, cold, drought, salt, and hypoxiap. 217
Herbivory and microbial infectionp. 226
Toxic substancesp. 234
Genomic approaches to ecological stress: an appraisalp. 243
Variation and adaptationp. 245
The internal tangled bankp. 245
Genomic polymorphismsp. 247
Regulatory and structural changep. 267
Epigenetic variation and developmental changep. 287
Genomic approaches to variation and adaption: an appraisalp. 300
Integrative ecological genomicsp. 302
The need for integration: systems biologyp. 302
Ecological control analysisp. 307
Outlookp. 311
Referencesp. 315
Indexp. 351
Table of Contents provided by Ingram. All Rights Reserved.

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