This book is the eagerly awaited Second Edition of the bestselling book widely acknowledged as the first modern, truly comprehensive work on mitochondria. Mitochondria, Second Edition brings readers up to date on the many significant findings that have occurred since the book was first published nearly a decade ago. As in that seminal first edition, this Second Edition tackles the biochemistry, genetics, and pathology of mitochondria in different organisms. The growth of the subject has required more emphasis on mammalian mitochondria, but fundamental new insights from other organisms are also included. The new edition provides thorough updates of all the literature concerning this vital organelle, its functions, ongoing research surrounding it, and its importance vis-a-vis a broad range of issues in cellular and molecular biology. Mitochondria, Second Edition includes detailed descriptions of current and developing technologies involved in mitochondrial research and discovery, and highlights subjects that are growing, such as the use of proteomics. Complete with black-and-white drawings and photographs, Mitochondria, Second Edition is an invaluable resource for all geneticists, biologists, and educators in the life sciences. It is also of interest to advanced students in genetics and molecular biology. Book jacket.

Immo E. Scheffler, PhD, is Professor in the Division of Biology (Molecular Biology Section) at the University of California, San Diego