Pharmaceutical Process Engineering, Second Edition

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Edition: 2nd
Format: Hardcover
Pub. Date: 2009-10-22
Publisher(s): CRC Press
List Price: $246.09

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Summary

With step-by-step methods of drug production and knowledge of major unit operations and key concepts of pharmaceutical engineering, this guide will help to improve communication among the varied professionals working in the pharmaceutical industry.Key features:REVISION OF A BESTSELLER - Updates include recent advances in the field to keep pharmaceutical scientists and technologists up-to-dateIDEAL INTRODUCTORY TEXT - Covers basic engineering principles, drug production, and development processes, so scientists can easily convert bulk pharmaceutical products into patient-ready dosage formsNEW INFORMATION - on quality principles that include quality by design; mathematical and statistical approaches to experimental design; computer aided design; and PAT (process analytical technology) keeps professionals at the forefront of their fieldCOMPREHENSIVE COVERAGE - Step-by-step methods of drug production, knowledge of major unit operations, and key concepts of pharmaceutical engineering will help to improve communication among the varied professionals working in the pharmaceutical industry

Author Biography

Anthony J. Hickey is Professor of Molecular Pharmaceutics and Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, and President and CEO of Cirrus Pharmaceuticals, Inc., Durham, North Carolina, USA; Founder and former Chief Scientific Officer of Oriel Therapeutics, Inc.; and Chair of the Aerosols Expert Committee of the United States Pharmacopeia. The author, coauthor, and coeditor of numerous journal articles, book chapters, and books, including Pharmaceutical Inhalation Aerosol Technology, Inhalation Aerosols, and A Guide to Pharmaceutical Particulate Science (all Informa Healthcare titles), he is Fellow of the Institute of Biology, the American Association of Pharmaceutical Scientists, and the American Association for the Advancement of Science. He received his B.Sc. degree (1977) from Portsmouth Polytechnic, UK; M.Sc. degree (1980) from the University of Birmingham, UK; and Ph.D. (1985) and D.Sc. (2003) degrees from Aston University, Birmingham, UK. David Ganderton was formerly Director, Vectura Limited, Bath, UK. Dr. Ganderton received his B. Pharm. and Ph.D. degrees from the University of London, London, UK. He is the author or coauthor of numerous journal articles, book chapters, and books. Dr. Ganderton is also Fellow of the Royal Pharmaceutical Society of Great Britain.

Table of Contents

Prefacep. vii
Acknowledgmentsp. ix
Units and Dimensionsp. xiii
Introductionp. 1
Fundamentals
Fluid Flowp. 4
Heat Transferp. 31
Mass Transferp. 46
Powdersp. 53
Processes
Air Conditioning and Humidificationp. 63
Dryingp. 68
Solid-Liquid Extractionp. 87
Crystallizationp. 92
Evaporation and Distillationp. 100
Filtrationp. 117
Size, Reduction and Classificationp. 136
Mixingp. 155
Solid Dosage Formsp. 168
Sterilizationp. 178
Bioprocessingp. 183
Quality Principles
Quality by Designp. 193
Statistical Experimental Designp. 197
Process Analytical Technologyp. 202
Conclusionp. 205
Referencesp. 207
Bibliographyp. 212
Indexp. 215
Table of Contents provided by Ingram. All Rights Reserved.

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